One of these methods will surely help you overcome the issue. This works in most cases, where the issue is originated due to a system corruption.
Nexus Mod Manager is free and open software that can help you install and uninstall mods easily. Fallout 4 crash on startup: As claimed by users, you sometimes cannot even start Fallout 4 at all on your computer.Fallout: London DLC-Sized Mod for Fallout 4 Announced With a New Trailer.